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pentobarbital will lessen the level or result of eplerenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.pentobarbital will lower the level or outcome of irinotecan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.You’ll have 24-hour supervision if you decide for inpatie